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Primary Contact |
Luis G. Aguayo, Ph.D. |
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Job
Title |
Professor |
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Phone
Number |
(56-41)
220 3380 |
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Fax Number |
(56-41) 224 5975 |
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Mobile Number |
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Organization Description

CIAB is dedicated to fundamental and applied
research in Cell Biology and its relation
to Biomedicine and Biotechnology, studying
challenging issues such as membrane transport,
signaling and control of gene activity in
development, cancer, alcoholism, as well
as in infectious and degenerative diseases.

The Center is developing a strong relationship
with health and pharmaceutical industries,
as well as with government organizations
to improve human health. Its scientists
carry out interdisciplinary studies on important
cellular functions in normal and diseased
cells using leading edge cellular and molecular
techniques.

Specifically, CIAB is examining several
membrane proteins that function as transporters
or receptors that receive external signals
and translate them into physiological responses.
Also studying intracellular regulation,
as well as second messengers in normal and
diseased stages in addition to the molecular
and genetic basis of neurodegenerative disases.
CIAB will put a significant effort into
the study of several genes that regulate
the expression of some of these proteins.

In addition to performing internationally
recognized leading edge research, the Center
will serve the Chilean community through
outcomes such as improved postgraduate education,
social benefit to Chileans (i.e., improved
education and health), and finding solutions
to major biomedical and biotechnological
problems of Chile.
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Strategic Direction

CIAB main strategy is to:
• Develop first-rate internationally
recognized Cellular and Molecular Biology
Research.
• Develop innovative under and post-graduate
education, as well as medical personnel
specialization.
• Participate in the nascent Chilean
biotechnology industry providing scientific,
administrative and regulatory “know-how”.
• Improve human health through diffusion
of knowledge acquired by research on high
prevalent diseases.
• Improve education by providing quality
training to high school teachers and students
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Products/Services
and Operations

The strength of CIAB resides in basic
science research in areas such as gene regulation,
membrane transport, neuroscience and pharmaceutical
development. The Center is developing new
diagnostic methodologies as well as updated
therapeutical application.

Four areas that are currently being developed:
• Production of new diagnostic tools
based on biological markers (SNPs).
• Research on novel Chilean natural
compounds for use in veterinarian and human
medicine.
• Research on novel and effective applications
of anti-oxidants for treatment of degenerative
disorders.
• New drug formulations.
The Centre is developing a core facility
to undertake clinical trials.
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Alliances with research centres,
universities and/or international consortiums
for R&D activities

Yes
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Government
Funding

CIAB and its members have received 12 FONDECYT
grants, 3 FONDEF grants, 5 Bicentennial
Program on Science and Technology grants
and 3 international grants.
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Affiliations

Affiliated to networks: Yes

Research Collaborations with Universities
and Institutions
• National Institute of Health, USA
• Universitatsklinikum Aachen, GERMANY
• Marquette University, USA
• Limburgs Universitair Centrum, BELGIUM
• University College of London, ENGLAND
• University of Massachusetts, USA
• Columbia University, USA
• Roswell Park Cancer Institute, USA
• Universidad Federal de Sao Paulo, BRAZIL
• University of Melbourne, AUSTRALIA.

Grants from International Agencies
• Fogarty International Research Center
• National Institutes of Health (NIH),
USA
• Human Frontier Scientific Program (HFSP).
• British Council-Conicyt.
• Bilateral Scientific Cooperation (Flanders
Belgium)

Grants From National Agencies
• FONDECYT
• FONDEF
• Programa Bicentenario Ciencia y Tecnologia.
Conicyt-Banco Mundial.
• FUNDACION ANDES
• MECE-SUP
• INNOVA BIO BIO

Affiliated with a particular institution or
industrial organizations: Yes

• Hospital Regional de Concepción.
• Asociacion Industrial de Laboratorios
Farmaceuticos de Chile (ASILFA).
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